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Founded in 1947, the Ministry of Science and Health of Rhineland-Palatinate (Ministerium für Wissenschaft und Gesundheit Rheinland-Pfalz) is a government ministry responsible for the development and implementation of policies related to science, research and health in the German state of Rhineland-Palatinate. Its main tasks include:
- Developing and implementing policies related to higher education, scientific research and health care.
- Overseeing and managing public universities, research institutions, hospitals and other health care institutions.
- Supporting and promoting scientific research and innovation.
- Developing policies and initiatives related to international cooperation in education, research and health care.

The Ministry of Science and Health of Rhineland-Palatinate works to ensure that all citizens of Rhineland-Palatinate have access to quality education, training opportunities and health care services. It seeks to promote the development of a skilled and knowledgeable workforce, as well as the advancement of scientific research and innovation in the state. Additionally, the Ministry may collaborate with other government agencies and organizations to achieve these goals, including the Federal Ministry of Education and Research and the German National Academy of Sciences Leopoldina.